Effect of selenium chrome lipid complex withChlorella vulgaris Biej. on the carbohydrate and lipid metabolism in experimental type 2 diabetes

Abstract

Through the incubation of single-celled alga Chlorella vulgaris Biej. in sodium selenite and chrome(III) chlo-ride aquaculture, selenium chrome lipid substance has been obtained, separated and tested on the rats with exper-imental type 2 diabetes. Diabetes was induced in 2 stages: 1) high-calorie diet+sodium glutamate for 4 weeks; 2) intraperitoneal introduction of streptozotocin (65 mg/kg), preceded by nicotinamide (230 mg/kg). When intro-duced to the rats with experimental diabetes in 1 ml of 1% starch and water suspension, selenium (0.6mcg), chrome (1.05mcg) and lipid (0.5 mg) have been found to decrease intoxication and improve carbohydrate and lipid me-tabolism both in the liver and blood serum, thus proving efficacy for diabetes prevention and treatment.